Pharmacological management of fluid overload

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Pharmacological management of fluid overload.

BACKGROUND Standard treatment practice for the hypotensive patient with poor tissue perfusion is rapid volume resuscitation; in some scenarios, such as septic shock, this is performed with targeted goal-directed endpoints within 6 h of presentation. As a result, patients often develop significant positive fluid accumulation, which has been associated with poor outcomes above certain thresholds....

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Fluid Overload

Despite its high prevalence and significant rates of associated morbidity and mortality, the syndrome of decompensated heart failure (HF) remains poorly defined and vastly understudied. HF is due to several mechanisms including pump dysfunction disorder, neurohormonal activation disorder, and salt-water retention disorder. The first step of the syndrome includes cardiac damage and remodeling in...

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Fluid overload in the ICU: evaluation and management

BACKGROUND Fluid overload is frequently found in acute kidney injury patients in critical care units. Recent studies have shown the relationship of fluid overload with adverse outcomes; hence, manage and optimization of fluid balance becomes a central component of the management of critically ill patients. DISCUSSION In critically ill patients, in order to restore cardiac output, systemic blo...

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Oliguria and fluid overload.

Oliguria is a very common clinical situation that is also often difficult to interpret since it may represent either the expression of a disease or an appropriate response of the kidneys to extracellular volume depletion or decreased renal blood flow. In patients with acute kidney injury, oliguria is independently associated with mortality. Fluid overload is a complication of the impaired sodiu...

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How to avoid fluid overload.

PURPOSE OF REVIEW This review highlights the recent evidence describing the outcomes associated with fluid overload in critically ill patients and provides an overview of fluid management strategies aimed at preventing fluid overload during the resuscitation of patients with shock. RECENT FINDINGS Fluid overload is a common complication of fluid resuscitation and is associated with increased ...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2014

ISSN: 0007-0912

DOI: 10.1093/bja/aeu299